Biochemical Profile of Renal Dysfunction in Type 2 Diabetes Mellitus: Insights from a Libyan Case-Control Study

April 14, 2026April 14, 2026 Selim

Biochemical Profile of Renal Dysfunction in Type 2 Diabetes Mellitus: Insights from a Libyan Case-Control Study

📘 : Nexus Global Research Journal of Medical Sciences (NGRJMS) Volume 2, Issue 2, 2026 (Page : 29 – 33)

ABSTRACT:

Diabetes mellitus significantly elevates the risk of renal impairment, characterized by abnormal levels of serum creatinine, urea, and other electrolytes. In this case-control study, we compared 84 type 2 diabetes mellitus (T2DM) patients (cases) with 20 healthy controls, finding 100% prevalence of abnormal blood urea and creatinine in cases versus none in controls (p<0.001) (1). Key correlations included positive associations between creatinine and HbA1c (rs=0.303, p=0.005), random blood sugar (RBS; rs=0.269, p=0.013), and serum phosphorus (rs=0.325, p=0.003). These findings underscore hyperglycemia’s role in diabetic kidney disease (DKD) progression, aligning with recent evidence on modifiable risk factors like poor glycemic control. Early biochemical screening is recommended for 2DM management to prevent end-stage renal disease (2,3). This study analyzes biochemical data from 84 diabetic patients and 20 controls, revealing strong associations between diabetes and renal dysfunction markers like elevated creatinine and urea (4,5,6).

Keywords: Diabetes, Renal dysfunction, and Biochemical markers, Glycated Hemoglobin

Impact of Urbanization on Public Health

April 14, 2026April 14, 2026 Selim

Impact of Urbanization on Public Health

: Peter F. Lang

🪪 : DOI: 10.5281/zenodo.18924773

📘 : Nexus Global Research Journal of Medical Sciences (NGRJMS) Volume 2, Issue 2, 2026 (Page : 34 – 40)

ABSTRACT:

This work shows the consequence of increased urbanization on the impact of pandemics and infectious diseases on public health especially in inner city areas. It demonstrates that the Covid-19 pandemic impacts particularly on large cities and urban areas. There have been many pandemics throughout history and they occurred mainly in cities. Mortality rates show vaccines are not 100% effective against all variants. The trend in increasing urbanization enhances the probability of more serious pandemics in the future with disparity against lower income inhabitants in inner cities. This work discusses ways which public health can be improved.

Keywords: Urbanization, Infection, Public Health. Pandemic

A Prospective Observational Study of Coagulation Profiles in Patients on Common Antithrombotic Therapies and Their Correlation with Bleeding Risk

April 14, 2026April 14, 2026 Selim

A Prospective Observational Study of Coagulation Profiles in Patients on Common Antithrombotic Therapies and Their Correlation with Bleeding Risk

: Ogonnaya Chinemerem Cynthia, Verla Evelyn Ngozi, Ugwulor Louis Oguchukwu, Verla Andrew Wirnkor, Achang Keneth Youngabi.

🪪 : DOI: 10.5281/zenodo.19044290

📘 : Nexus Global Research Journal of Medical Sciences (NGRJMS) Volume 2, Issue 2, 2026 (Page : 41 – 47)

ABSTRACT:

Antithrombotic therapies including warfarin and antiplatelet agents require careful monitoring to balance thrombotic protection against bleeding risk. This is particularly challenging in resource-limited settings where access to specialized coagulation testing is often restricted. A prospective observational study was conducted from January to December 2023 at three tertiary care hospitals in Nigeria. We enrolled 450 patients on stable antithrombotic therapy (150 on warfarin, 150 on aspirin, 150 on clopidogrel) and followed them for six months. Prothrombin time/international normalized ratio (PT/INR), activated partial thromboplastin time (aPTT), and bleeding events were monitored monthly. Among warfarin patients, only 42.7% maintained therapeutic INR ranges (2.0-3.0) across all measurements, while 34.0% showed subtherapeutic and 23.3% supratherapeutic values. The incidence of major bleeding was significantly higher in patients with INR >3.5 (18.9% vs. 2.3% in therapeutic range, p<0.001). Antiplatelet therapy patients demonstrated minimal changes in conventional coagulation parameters despite clinically significant bleeding events. Multivariate analysis identified age >65 years (OR: 3.2, 95% CI: 1.8-5.7), renal impairment (OR: 2.8, 95% CI: 1.5-5.2), and concomitant NSAID use (OR: 2.4, 95% CI: 1.3-4.4) as independent predictors of bleeding Basic coagulation tests effectively stratify bleeding risk in warfarin-treated patients but have limited utility for monitoring antiplatelet therapies. Simplified risk assessment tools incorporating clinical factors and basic laboratory parameters can optimize antithrombotic management in settings with limited resources.

Keywords: Antithrombotic, Antiplatelet agents, Bleeding risk, Coagulation profiles, INR monitoring, Resource-limited settings, Warfarin

Rising Seas and Shifting Lives: An Ecocritical Reading of Amitav Ghosh’s Gun Island

April 13, 2026April 17, 2026 Selim

Rising Seas and Shifting Lives: An Ecocritical Reading of Amitav Ghosh’s Gun Island

: Ms. C. Mobisha Keni, Dr. A. Annie Divya Mahisha.

🪪 : DOI: 10.5281/zenodo.18296323

📘 : Nexus Global Research Journal of Art’s, Humanities (NGRJAH) Volume 2, Issue 1, 2026 (Page : 01 – 07)

ABSTRACT:

This paper offers an ecocritical reading of Amitav Ghosh’s Gun Island focusing on the interconnected crises of rising seas, climate change and human displacement. Set against transnational landscapes stretching from the Sundarbans to the Mediterranean, the novel foregrounds how environmental degradation reshapes both ecosystems and human lives. Through an ecocritical lens, the study examines the fragile relationship between humans and the non-human world, highlighting how climate-induced disasters such as cyclones, sea-level rise and biodiversity loss disrupt traditional livelihoods and force migration. Ghosh portrays nature not as a passive backdrop but as an active agent that challenges anthropocentric assumptions and exposes the ethical responsibilities of humanity toward the planet. The novel’s blending of myth, history and contemporary climate realities underscores ecological memory and the interconnectedness of global ecological systems. This paper argues that Gun Island urges readers to recognize climate change as a shared, transboundary crisis and calls for ecological awareness, empathy and sustainable coexistence in an era of accelerating environmental uncertainty.

Keywords: Ecology, Equilibrium, Resistance, Anthropocene, Exploitation

Margins to Movements: Social Innovation and Diffusion of AlternativeCommunities in Arundhati Roy’s The Ministry of Utmost Happiness

April 13, 2026April 15, 2026 Selim

Margins to Movements: Social Innovation and Diffusion of AlternativeCommunities in Arundhati Roy’s The Ministry of Utmost Happiness

: Ms. T. Vathana, Dr. A. Annie Divya Mahisha.

🪪 : DOI: 10.5281/zenodo.18297039

📘 : Nexus Global Research Journal of Art’s, Humanities (NGRJAH) Volume 2, Issue 1, 2026 (Page : 08 – 14)

ABSTRACT:

This paper examines Arundhati Roy’s The Ministry of Utmost Happiness through the lens of Everett Rogers’ Diffusion of Innovations theory, focusing on how marginalized communities generate and disseminate social innovations that challenge dominant power structures. The novel portrays alternative communities—formed by hijras, political dissidents, Dalits and Kashmiri voices—as innovative social systems that resist exclusion and reimagine belonging. These communities function as grassroots innovations that emerge from lived experiences of oppression, gradually diffusing their values of care, coexistence and resistance across hostile social environments. Applying key concepts of diffusion theory—innovation, communication channels, opinion leaders, time and social systems—the study analyses how narrative acts as a medium for transmitting counter-hegemonic ideas to wider audiences. Characters such as Anjum and Tilo operate as change agents, facilitating slow but transformative social adoption. The paper argues that Roy’s novel redefines innovation not as technological advancement, but as ethical, communal and political imagination, demonstrating literature’s potential to mobilize social change from the margins to collective movements within postcolonial India’s fractured public sphere. Such narratives invite readers to rethink justice, citizenship, empathy, solidarity and inclusive futures globally.

Keywords: Survival, Hijra, Culture, Identity, Community

Decline of Eschatological Consciousness in Contemporary Churches: Causes and Consequences

April 13, 2026April 15, 2026 Selim

Decline of Eschatological Consciousness in Contemporary Churches: Causes and Consequences

: Okoi, Bassey John, Onen, Ruth Moses, Eni, William Ibiang.

🪪 : DOI: 10.5281/zenodo.18459176

📘 : Nexus Global Research Journal of Art’s, Humanities (NGRJAH) Volume 2, Issue 1, 2026 (Page : 15 – 22)

ABSTRACT:

Eschatological consciousness over the years has functioned as an important framework shaping Christian hope, way of behaviour, worship, and mission. Based in biblical theology, eschatology guide believers toward God’s ultimate purposes for history and the realization of His kingdom. However, in many contemporary churches, there is a noticeable decline in eschatological consciousness, reflected in diminished emphasis on themes such as Christ’s return, divine judgment, resurrection, and eternal destiny. This study therefore examines the theological meaning of eschatological consciousness and traces its significance within Old and New Testament traditions, highlighting its role in sustaining faith amid suffering and oppression. Using a conceptual and theological analysis, the study considered key factors contributing to its decline, including secularization, prosperity-oriented and therapeutic theologies, pragmatic church growth models, and fears arising from apocalyptic abuses. The study further identifies the consequences of this decline, particularly the weakening of Christian hope, moral complacency, distortion of mission, and theological imbalance. Finally, the study argues for a recovery of eschatological consciousness through biblically grounded teaching, liturgical renewal, ethical engagement, and contextual theological formation. It concludes that reclaiming eschatological consciousness is important for restoring theological depth, moral accountability, and resilient hope within contemporary Christian communities.

Keywords: Eschatological Consciousness, Christian Hope, Contemporary Churches, Biblical Eschatology, Theological Renewal

Strengthening Primary Mathematics Education: Challenges, Opportunities and Implications for Teaching Practice in Timor-Leste

April 13, 2026April 15, 2026 Selim

Strengthening Primary Mathematics Education: Challenges, Opportunities and Implications for Teaching Practice in Timor-Leste

: Salvador Magno Ximenes.

🪪 : DOI: 10.5281/zenodo.18459176

📘 : Nexus Global Research Journal of Art’s, Humanities (NGRJAH) Volume 2, Issue 1, 2026 (Page : 23 – 32)

ABSTRACT:

The review analyses educational difficulties alongside teaching possibilities that arise within Timor-Leste’s primary school mathematics education. Many barriers obstruct effective mathematics teaching despite extensive school improvement initiatives, such as creating problems with unqualified teachers and limited educational resources, which make student understanding complex because of language barriers. The post-conflict recovery context of Timor-Leste presents more difficulties for the educational system because it has damaged the school infrastructure and teacher development processes. Recent structures of curriculum reform target the modernization of teaching techniques with peer collaborative initiatives that support educator professional development as administrative forces advance mother tongue-based educational programs for increased student comprehension through native language instruction. This review combines information from various studies about the current mathematics education status of Timor-Leste, which helps policy leaders and education professionals gain important knowledge. The mathematics education system of Timor-Leste requires special interventions that combine competent teacher training with appropriate financial resources to support teachers in resolving existing difficulties while utilizing language effectively for developmental gains.

Keywords: Mathematics education, teacher training, teaching practice and primary schools

E-Governance for Transparency and Youth Democratic Engagement: A Comparative Study

April 13, 2026April 13, 2026 Selim

E-Governance for Transparency and Youth Democratic Engagement: A Comparative Study

: Muhammad Umar Farooq, Ahsan yousaf.

🪪 : DOI: 10.5281/zenodo.17988171

📘 : Nexus Global Research Journal of Multidisciplinary (NGRJM) Volume 1, Issue 4, 2025 (Page : 201 – 209)

ABSTRACT:

The central objective of this paper is to examine the capacity of contemporary governance systems to employ digital technology for enhancing transparency and straightening youth democratic engagement. Digital governance has emerged as a tool for improving public sector accountability, reducing corruption, and creating new opportunities for civic participation. This research approaches to explore how different countries utilize digital platforms like open data systems, online service portals, and youth engagement, to enhance transparency, improve decision making and integrate young citizens in democratic processes.In the context of Pakistan, the study highlights the critical significance of digital tools in addressing the country’s complex governance challenges. Many citizens rely on digital platforms such as the Pakistan Citizen Portal, open-budget dashboards, and youth-focused digital initiatives to improve transparency and reconnect young people with democratic processes. These developments highlight both the opportunities and the challenges associated with adopting e-governance reforms in an emerging democracy. Digital governance has emerged as a tool for improving public sector accountability and creating opportunities for youth civic participation (UN E-Government Survey, 2022).
Keywords: Contemporary Governance Systems, Digital Technologies, Transparency, Democratic Engagement

Exploring Patient Attitude on Adoption of Artificial Intelligence in Diabetes Care

April 13, 2026April 13, 2026 Selim

Exploring Patient Attitude on Adoption of Artificial Intelligence in Diabetes Care

: Usman Abdullahi, Abubakar Sadiq Bunu.

🪪 : DOI: 10.5281/zenodo.17987458

📘 : Nexus Global Research Journal of Multidisciplinary (NGRJM) Volume 1, Issue 4, 2025 (Page : 210 – 216)

ABSTRACT:

The adoption of Artificial intelligence (AI) into diabetic care has a potential to improve patient management especially in Nigeria, where diabetes poses a serious health challenge. The effectiveness of AI in patient management significantly depends on patient attitude. The paper addresses the gap in understanding the attitude of diabetic patients toward AI. The aim is to study the perspective of patient on the use of AI technologies and applications in managing diabetes. This study examines the patterns of acceptance and understanding of AI among diabetic patients. Qualitative data using interview with diabetic patient at diabetic clinic of Federal Teaching Hospital Gombe, was collected. Thematic analysis was performed in accordance with established standard for data analysis. The data revealed three central themes related to their attitudes toward the use of artificial intelligence in managing diabetes which are perceived acceptability, recognized advantages of AI tools, and the perceived necessity for such technologies. Most participants shared favorable opinions about incorporating AI into diabetes care. These results provide a foundation for developing a theoretical model to better understand how patients view AI in this context, highlighting the influence of their health experiences, technological familiarity, and social factors.

Keywords: Artificial Intelligence, Diabetes, Health management, Patient attitude

Post-Harvest Handling and Consumption Practices of Fruits and Vegetables: Implications for Maternal Nutrition During Pregnancy and Postpartum Among Teenage Mothers in Rural Districts of Ghana

April 13, 2026April 13, 2026 Selim

Post-Harvest Handling and Consumption Practices of Fruits and Vegetables: Implications for Maternal Nutrition During Pregnancy and Postpartum Among Teenage Mothers in Rural Districts of Ghana

: Azumah Lariba Cecilia , Mohammed Ali.

🪪 : DOI: 10.5281/zenodo.17987620

📘 : Nexus Global Research Journal of Multidisciplinary (NGRJM) Volume 1, Issue 4, 2025 (Page : 217 – 230)

ABSTRACT:

Pregnancy and postpartum maternal nutrition is a major driver influencing maternal and child health. In rural Ghana, teenage mothers are confronted with distinct nutritional challenges that stem from poverty, lack of autonomy, and poor food handling and storage facilities. Post-harvest consumption behaviors of fruits and vegetables among teenage mothers in MampruguMoaduri, West Mamprusi, and East Mamprusi districts and their impact on mothers’ nutrition were investigated in this study. A prospective longitudinal mixed-methods design was used with quantitative surveys, as well as qualitative interviews and focus group discussions. Three hundred teenage mothers aged 13–19 years were chosen for the study based on multi-stage sampling. Results showed high dependence on locally obtained fresh fruit and vegetables during peak seasons with modest storage capacities. Wild sources, including shea fruit and baobab leaves, supplemented diets but were consumed on a seasonal basis. Also, handling practices for fruits were dominated by immediate consumption, and 66.5% and 74.2% of fruits and vegetables were consumed within the same day, respectively. Better storage protocols (e.g., drying or refrigeration) were less common (<9%), but were associated with higher dietary diversity scores (p < 0.05). Improved storage practices were positively associated with education level (χ² = 12.4, p < 0.01). Qualitative studies revealed economic constraints, cultural beliefs, and infrastructural hurdles as hindrances to fruit and vegetable consumption. This study fills in the gaps in the literature by focusing on teenage mothers, a group that is rarely examined in maternal nutrition literature. In deprived rural settings, findings highlight the necessity of context-appropriate interventions, such as increased storage technologies, nutritional education, and livelihood support to improve dietary diversity and maternal health outcomes in these rural districts.

Keywords: Teenage mothers, Maternal nutrition, Post-harvest handling, Dietary diversity and Food security